Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

The 1% solution of povidone-iodine is considered safe for use on wounds without harming fibroblasts, which are essential cells involved in wound healing. At this lower concentration, the antiseptic properties are effective against bacteria while minimizing cytotoxic effects on surrounding tissues, including fibroblasts. In contrast, higher concentrations often found in scrubs, gels, or concentrated solutions can have detrimental effects on fibroblast activity, potentially impairing the healing process. Scrubs are typically designed for skin cleansing and can cause tissue irritation. Gels may contain higher concentrations of povidone-iodine, posing similar risks to cell viability. Concentrated solutions, while highly effective as antiseptics, are also notably harmful to fibroblasts and should be used with caution in wound care. Using a 1% solution balances antimicrobial efficacy with the preservation of essential cells required for healing, making it the preferred choice in clinical practice when treating wounds.