Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

How can the negative effects of corticosteroids on wound healing be managed?

1. Reduce hydration

2. Apply topical antibiotics only

3. Administer 25-100k IU of vitamin A on the wound bed

4. Increase physical activity

The correct answer is: Administer 25-100k IU of vitamin A on the wound bed

The management of the negative effects of corticosteroids on wound healing can effectively be addressed by administering 25-100k IU of vitamin A on the wound bed. Corticosteroids can impair wound healing by inhibiting fibroblast proliferation and collagen synthesis, which are critical factors in the healing process. Vitamin A plays a crucial role in skin health and wound healing; it is involved in epithelialization and has been shown to enhance collagen formation and tissue repair. By applying vitamin A to the wound bed, it supports cellular functions that are essential for effective healing, thus counteracting some of the inhibitory effects of corticosteroids. This approach can promote faster and more efficient wound healing, particularly in a patient who may be using corticosteroids for their underlying condition. Other strategies mentioned, such as increasing hydration or applying topical antibiotics, do not specifically address the influence of corticosteroids on wound healing. For example, reducing hydration can actually lead to problems, as adequate moisture is important for optimal healing. While antibiotics may prevent infections, they do not counteract the adverse effects of corticosteroids on tissue regeneration and repair. Additionally, increasing physical activity might have other benefits, but it does not directly influence the biochemical pathways affected by corticosteroids in the context of wound healing. Thus, utilizing