Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

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How is becaplermin gel applied to a wound?

  1. For 12 hours daily followed by an extended dry period

  2. For 12 hours daily followed by moist saline gauze for another 12 hours

  3. Once weekly for a total of 24 hours

  4. Continuously until the wound is healed

The correct answer is: For 12 hours daily followed by moist saline gauze for another 12 hours

Becaplermin gel, which is a recombinant human platelet-derived growth factor, is indicated for the treatment of certain types of chronic wounds, particularly diabetic ulcers. The application of this gel is typically designed to promote healing by stimulating cell proliferation and migration. The correct method of application involves applying the gel for 12 hours daily, creating a moist environment that is conducive to healing. After this period, moist saline gauze is used for another 12 hours. This approach not only ensures that the wound remains hydrated during the active application of the gel but also allows for a controlled environment that can reduce the risk of infection and further promote healing. This method takes into account the physiological processes involved in wound healing, particularly the need for moisture and the role of growth factors in facilitating tissue repair. Using moist saline gauze after the initial gel application helps maintain necessary moisture levels in the wound bed while providing a barrier to external contaminants. The other methods mentioned do not align with the best practices for applying becaplermin gel. Continuous application without breaks could lead to excess accumulation of the gel, while long intervals between applications or less frequent application do not provide the sustained pharmacological benefits that the gel is meant to offer. Hence, the correct choice supports optimal wound healing in a