Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

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What are the two types of MMP inhibitors mentioned?

  1. Silver-based ointments and collagen matrix.

  2. Collagen-ORC matrix products and PHI ointment.

  3. Hydrogen ointment and saline solutions.

  4. Synthetic dressings and fluid-absorbing agents.

The correct answer is: Collagen-ORC matrix products and PHI ointment.

The correct answer highlights the two types of matrix metalloproteinase (MMP) inhibitors, specifically the collagen-ORC (oxidized regenerated cellulose) matrix products and PHI (protease inhibited) ointment. MMP inhibitors play a significant role in wound healing by modulating the activity of MMPs, enzymes that can degrade extracellular matrix components. The collagen-ORC matrix products provide a structural foundation and support for healing while simultaneously inhibiting MMP activity, thus preventing further breakdown of essential tissue elements. Similarly, PHI ointment contains elements that protect the wound from the activity of MMPs, aiding in the maintenance of an optimal healing environment. Other options contain products that do not specifically function as MMP inhibitors or do not represent known classes associated with this therapeutic strategy. Understanding the functions of these specific products is essential for effective wound care management.