Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

What happens during granulation tissue formation?

1. Fills tissue defect with scar tissue

2. Increased inflammation in the wound area

3. Formation of necrotic tissue

4. Reduction of blood supply to the wound

The correct answer is: Fills tissue defect with scar tissue

Granulation tissue formation is a crucial part of the wound healing process, specifically during the proliferative phase. During this stage, new tissue is generated to replace the temporary fibrin clot that initially forms after injury. Granulation tissue is characterized by an abundance of new capillaries (angiogenesis), collagen deposition, and the presence of inflammatory cells which facilitate healing. When granulation tissue fills a tissue defect, it provides a scaffold for further healing and subsequent epithelialization. This newly formed tissue is rich in blood vessels, which supply essential nutrients and oxygen to the area, pivotal in maintaining a dynamic healing environment. The process ultimately leads to a reduction in wound size and serves as a foundation for scar tissue development. Other options describe processes that are either not part of granulation tissue formation or that occur in different contexts. Thus, the correct answer accurately captures the essence of granulation tissue and its role in wound healing.