Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

Which treatment is suggested for hypertrophic granulation tissue?

1. Topical antibiotics

2. AgNO3 or mid-potency steroid

3. Silicone gel sheets

4. Hydrogel dressings

The correct answer is: AgNO3 or mid-potency steroid

Hypertrophic granulation tissue is characterized by excessive tissue growth that can occur during the healing process. To effectively manage this condition, treatments aimed at reducing the hyperplastic response and promoting normal healing are necessary. Using AgNO3 (silver nitrate) or mid-potency steroids is effective because these agents have anti-inflammatory and cytotoxic properties. Silver nitrate, when applied directly, helps cauterize excessive granulation tissue, leading to necrosis of the tissue and subsequent reduction in its volume. Mid-potency steroids can help modulate inflammation and inhibit excessive fibroblast activity, promoting a more balanced healing process. In contrast to this, topical antibiotics, while essential for preventing infection, do not address the underlying problem of excessive tissue formation. Silicone gel sheets can help with the maturation of scars but may not be effective in directly reducing hypertrophic granulation tissue at an early stage. Hydrogel dressings are primarily used for maintaining moisture and facilitating autolytic debridement, but they do not specifically target the reduction of hypertrophic granulation tissue. Hence, the recommendation of AgNO3 or mid-potency steroids provides a targeted approach to manage this condition effectively.